Problema de desconexión del servidor con aplicación web activa

Se levanto un servidor usando Node.js utilizando Express y como gestor de base de datos MySQL.
Cada día parece perder la conexión a base de datos y lanzar una excepción que detiene el servidor.

La conexión se realiza usando un PoolConnection: var connection = mysql.createPool(dbconfig.connection);

Y la excepción es:


events.js:141
      throw er; // Unhandled 'error' event
      ^

Error: Connection lost: The server closed the connection.
    At Protocol.end (\node_modules\mysql\l
ib\protocol\Protocol.js:109:13)
    at Socket.<Anonymous> (\node_modules\m
ysql\lib\Connection.js:102:28)
    at emitNone (events.js:72:20)
    at Socket.emit (events.js:166:7)
    at endReadableNT (_stream_readable.js:913:12)
    at nextTickCallbackWith2Args (node.js:442:9)
    at process._tickCallback (node.js:356:17)

npm ERR! Windows_NT 6.3.9600
npm ERR! argv "C:\\Program Files\\nodejs\\node.exe" "C:\\Program Files\\nodejs\\
node_modules\\npm\\bin\\npm-cli.js" "start"
npm ERR! node v4.4.2
npm Err! npm  v2.15.0
npm err! code elifecycle
npm err! i@0.0.0 start: `node ./Bin/www`
npm ERR! Exit status 1
npm err!
npm err!  start script 'node ./Bin/www'.
Npm ERR! This is most likely a problem with the I package,
npm ERR! not with npm itself.
Npm ERR! Tell the author that this fails on your system:
npm ERR!    node ./Bin/www
npm ERR! You can get information on how to open an issue for this project with:
npm ERR!    npm bugs I
npm ERR! Or if that isn't available, you can get their info via:
npm err!
npm err!    npm owner ls i
npm err! there is likely additional logging output above.

Npm ERR! Please include the following file with any support request:
npm ERR!    C:\Program Files\iisnode\www\I\npm-debug.log


Si tienen experiencia con este tipo de problemas quisiera  una solución simple y estable, escucho propuestas. Saludos